Farmakológia

Ošetrovateľské techniky a zručnosti

General pharmacology and prescription

1. Signatura in the prescription is related to:

a) patient´s name, address, native number, health insurance of company

b) directions to the dispensing pharmacist to supply medication

c) directions to the patient in taking the medicine

d) the validity of the prescription

2. Generally, validity of the prescription for opioids (§) is:

a) 3 days
b) 7 days
c) 5 days
d) 24 hours

3. Mark the correct answer related to the prescription of extemporaneous eye ointments:

a) if the weight is under 0.3 g we have to add either lactose or sucrose
b) Unguentum ophthalmicum emulsificans is used as the eye ointment base
c) eye ointments are not sterilized
d) the total amount of eye ointment is 50 g

4. „Sub signo veneni“ in the prescription means:

a) label as a poison
b) write original name of the drug on the label
c) write the drug composition on the label of the drug
d) neither of these answers are correct

5. In the case of opioids (§) prescription you have to write out:

a) 1 original
b) 1 original + 1 copy
c) 1 original + 2 copies
d) 11 original + 3 copies

6. The extemporaneous drugs for external use are marked with:

a) white label
b) red label
c) green label
d) blue label

7. Morphine therapy withdrawal is associated with many unpleasant symptoms. These symptoms can be categorized as side effects:

a) type B (bizarre)
b) type A (augmented)
c) type E (ending)
d) type C (continuous)

8. Therapeutic index is expressed as a ratio between TD_50/ED₅₀.

a) Yes
b) No

9. Acidification of urine:

a) accelerates elimination of weak acids
b) accelerates elimination of weak base
c) doesn’t influence rate of drug elimination
d) any answer is correct

10. Which of the following process does not belong to pharmacokinetics?

a) absorption
b) distribution
c) drug-receptor interaction
d) excretion

11. Choose a correct completion of the statement: For an active transportation is characteristic that:

a) it does not require energy
b) it works against concentration gradient
c) it does not require specific transporters
d)it works in the direction of concentration gradient

12. Choose a correct completion of the statement: For p-glycoprotein transporters and transporters responsible for polyresistance of cancer cells is characteristic that:

a) they do not require ATP for their activity
b) they act only in the direction of concentration gradient
c) they are present in various organs, including kidneys, liver and brain
d) they belong to the transporters enabling facilitated diffusion

13. Choose a correct completion of the statement: The result of inducing the liver enzymes from complex of P450 cytochrome is:

a) acceleration of metabolism of their substrate
b) slowing of metabolism of their subsrtate
c) increase in the level of drug, which is their substrate
d) decrease of the level of a drug, which a result of their activity on pro-drug

14. Choose a correct statement about calculation of maintenance or loading dose:

a) maintenance dose is dependent on drug clearance
b) loading dose is dependent on drug clearance
c) loading dose is dependent on protein binding of the drug
d) maintenance dose is dependent on distribution volume of the drug

15. Choose, which of the following interactions of warfarin belongs to pharmacodynamic interactions:

a) reduced plasma protein binding due to acetylsalicylic acid
b) supplementation of vitamin K in food
c) slower metabolism by liver P450 cytochrome
d) none of them is correct

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