Bones 1

A 58-yr-old postmenopausal woman was sent for dual-energy x-ray absorptiometry to evaluate the bone mineral density of her lumbar spine, femoral neck, and total hip. The test result revealed significantly low bone mineral density in all sites.

Questions and tasks

1. Chronic use of which of the following medications is most likely to have contributed to this woman`s osteoporosis?

a.      Lovastatin
b.      Metformin
c.       Prednisone
d.      Propranolol
e.      Thiazide diuretics

2. If this patient began oral therapy with alendronate, she would be advised to drink large quantities of water with the tablets and remain in an upright position for at least 30 min and until eating the first meal of the day. These instructions would be given to decrease the risk of which of the following?

a.      Cholelithiasis
b.      Diarrhea
c.       Constipation
d.      Erosive esophagitis
e.      Pernicious anemia

3. The patient`s condition was not sufficiently ontrolled with alendronate, so she began therapy with nasal spray containing a protein that inhibits bone resorption. The drug contained in the nasal spray was which of the following?

a.      Calcitonin
b.      Calcitriol
c.       Cinacalcet
d.      Cortisol
e.      Teriparatide

 

Solution